Moonshots with Peter Diamandis - The Moonshots Podcast Guide

About

Peter H. Diamandis — Moonshots on YouTube

The name "Moonshots" belongs to three different shows — and the flagship is Moonshots with Peter Diamandis, the weekly technology podcast from XPRIZE founder Peter H. Diamandis that tracks how exponential technology is reshaping humanity.

Hosted by Diamandis alongside Salim Ismail, Dave Blundin, and Alexander Wissner-Gross, the show reaches an audience of over 1 million entrepreneurs and innovators worldwide, with guests including Elon Musk, Cathie Wood, Ray Kurzweil, and Emad Mostaque. Its focus: artificial intelligence, the singularity, longevity, space exploration, and energy breakthroughs. (diamandis.com/podcast)

Three Shows, One Name

All three are worth your ears. The difference is what you want to get out of them.

1 · Moonshots with Peter Diamandis

Tech + the future of everything. Weekly two-hour conversations with builders, investors, and technologists on AI, the singularity, longevity, space, and energy. Recent guests: Elon Musk, Cathie Wood, Ray Kurzweil, Emad Mostaque.

YouTube · Apple Podcasts · Spotify

2 · Moonshots Podcast: Learning Out Loud

Personal growth + performance. Mike and Mark deconstruct the mindsets, daily habits, and secrets of the world's most successful thinkers and entrepreneurs. Recent topics: working with AI as a thinking partner (Ethan Mollick's frameworks), training your imagination, and turning pain into purpose.

Moonshots.io

3 · The Moonshot Podcast (Google X)

Radical invention, behind the scenes. Hosted by the "Captain of Moonshots" Astro Teller, this series from X, The Moonshot Factory chronicles the untold stories of radical innovations — the highs and the catastrophic lows of building early tech: energy kites, robotic pants, digital immune systems, and sea fuel.

x.company · Apple Podcasts · YouTube Playlist

Show History & Format

Moonshots began life as Moonshots and Mindsets — the name grew naturally out of Diamandis' philosophy that humanity's biggest problems get solved when we aim for goals that sound "impossible." After the rebrand to Moonshots with Peter Diamandis, the format stayed: a weekly, news-driven conversation with the full crew, usually running around two hours, with a back catalog that has already passed 279 episodes on the main channel (YouTube playlist).

The show's signature is the "WTF just happened in tech" roundup, where the four Mates spin through the week's biggest stories — frontier-model releases, robotics, energy, space, and longevity science — and argue about what actually matters. Those segments age well because they capture each story at the moment it broke, then add context from four very different operating perspectives: entrepreneur (Blundin), organizational strategist (Ismail), scientist (Wissner-Gross), and physician-entrepreneur (Diamandis).

Guest interviews are the show's second pillar, and the guest list reads like a who's who of the exponential era: Elon Musk, Cathie Wood, Ray Kurzweil, Emad Mostaque, and Michael Saylor — plus Jared Isaacman, whose EP #274 appearance covered NASA's moon base by 2028, Optimus robots on the Moon, and a 15-year Mars timeline (all episodes).

The show also meets its audience in person: Moonshots Live 2026 takes place September 25, 2026 in Los Angeles — Peter and the Mates gather a room of builders, creators, and optimists working to steer humanity toward an extraordinary future (Moonshots Live 2026 trailer).

Quick Facts

Show	Moonshots with Peter Diamandis (formerly Moonshots and Mindsets)
Hosts	Peter H. Diamandis with Salim Ismail, Dave Blundin, Alexander Wissner-Gross
Format	Weekly video podcast, roughly two hours per episode
Audience	1 million+ entrepreneurs and innovators
Focus	AI, the singularity, longevity, space exploration, energy
Recent guests	Elon Musk, Cathie Wood, Ray Kurzweil, Emad Mostaque
Where to listen	YouTube (@peterdiamandis), Apple Podcasts, Spotify
Other shows named Moonshots	Learning Out Loud (Mike & Mark); The Moonshot Podcast (Google X, Astro Teller)

Meet the Hosts

The four regulars behind the table — plus the show's most frequent guest. Photos and bios from Wikipedia and each host's own site.

Peter H. Diamandis

Host

American engineer, physician, and entrepreneur — founder and chairman of the XPRIZE Foundation and co-founder and executive chairman of Singularity University (Wikipedia). With Steven Kotler he wrote Abundance, Bold, and The Future Is Faster Than You Think, and in 2025 published the Longevity Guidebook. On Moonshots he is the anchor, opening every episode with the week's exponential-tech news and an abundance mindset.

Salim Ismail

Host

Indo-Canadian serial entrepreneur, angel investor, and technology strategist. He was the founding executive director of Singularity University and lead author of the bestseller Exponential Organizations, and joined the XPRIZE Foundation board in 2017 (Wikipedia). Today he also founded OpenExO, a general partner at Exponential Venture Capital, and brings the organizational-singularity lens to every story.

Dave Blundin

Host

Serial entrepreneur and founder and managing partner of Link Ventures. A graduate of MIT's AI Lab and one of the first ten employees at MicroStrategy, he has co-founded 23 companies — at least five with valuations over $100M — including Vestmark, which manages over $2 trillion in U.S. assets (Link Ventures). His 1992 MIT-era work on neural-network quantization earned him the nickname "godfather of quantization."

Alexander Wissner-Gross

Host

American research scientist and entrepreneur. He earned S.B. degrees in physics, electrical engineering, and mathematics from MIT — the last student to triple-major before the option was discontinued — and holds a Ph.D. in physics (Wikipedia). He is the founder of AI ventures lab Reified, and the show's resident scientist: he called AI's spread from math into physics, chemistry, and medicine episodes before it happened.

Emad Mostaque

Frequent Guest

British-Bangladeshi businessman, mathematician, and former hedge fund manager — co-founder and, until March 2024, CEO of Stability AI, the company behind Stable Diffusion (Wikipedia). Today he leads Intelligent Internet and wrote The Last Economy. Emad is Moonshots' most recurring guest, showing up on the AI-news panels from EP #199 to EP #282 (embedded above).